Conscientiousness predicts disease progression (CD4 number and viral load) in people living with HIV
Identifieur interne : 002131 ( Main/Exploration ); précédent : 002130; suivant : 002132Conscientiousness predicts disease progression (CD4 number and viral load) in people living with HIV
Auteurs : Conall O'Cleirigh [États-Unis] ; Gail Ironson [États-Unis] ; Alexander Weiss [États-Unis] ; Paul T. Jr Costa [États-Unis]Source :
- Health psychology : (Hillsdale, N.J.) [ 0278-6133 ] ; 2007.
Descripteurs français
- Pascal (Inist)
- Antigène CD4, Attitude consciencieuse, Cellule helper, Charge virale, Coping, Développement maladie, Etat dépressif, Etats Unis, Etude longitudinale, Evolution, Facteur prédictif, Développement maladie, Evolution, Facteur psychosocial, Homme, Lymphocyte T, Modèle en cinq facteurs de la personnalité, Observance médicamenteuse, Personnalité, SIDA, Santé mentale, Sous population cellulaire, Stress, Virus immunodéficience humaine, Personnalité, Charge virale, Lymphocyte T, Sous population cellulaire, Cellule helper, Stress, Coping, Etat dépressif, Observance médicamenteuse, Etude longitudinale, Santé mentale, Etats Unis, Homme, Facteur psychosocial, Antigène CD4, Attitude consciencieuse, Modèle en cinq facteurs de la personnalité.
- Wicri :
- topic : Homme, Santé mentale, Homme.
English descriptors
- KwdEn :
- AIDS, Big Five personality model, Cell subpopulation, Conscientiousness, Coping, Depression, Disease development, Drug compliance, Evolution, Follow up study, Helper cell, Human, Human immunodeficiency virus, Mental health, Personality, Predictive factor, Psychosocial factor, Stress, T-Lymphocyte, United States, Viral load.
Abstract
Objective: Psychosocial factors (e.g., depression, avoidant coping, life stress) have been related to disease progression in HIV. This study examined the relationship between the Big Five Conscientiousness factor and HIV disease progression (CD4 cell and viral load) over 1 year in 119 seropositive participants. The study also examined whether Conscientiousness effects were mediated by adherence, perceived stress, depression, or coping measures. Design: In a 1-year longitudinal design, participants completed the NEO Five-Factor Inventory Conscientiousness scale (P. T. Costa & R. R. McCrae, 1992). Participants also completed psychosocial assessments and underwent blood draws at initial assessments and 1-year follow-up. Main Outcome Measures: Multiple hierarchical regression models were used to predict change in CD4 cell numbers and viral load log 10, controlling for demographic variables, initial disease status, and antiretroviral medications. Results: Conscientiousness predicted significant increases in CD4 number and significant decreases in viral load at 1 year. Conscientiousness was related positively to medication adherence and active coping and negatively to depression and perceived stress. Only perceived stress emerged as a possible mediator. Conclusion: The significant relationship between Conscientiousness and medication adherence, distress, and coping suggests that an assessment of Conscientiousness in patients with HIV may help specify or target behavioral interventions to promote optimal disease management.
Affiliations:
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Le document en format XML
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Jr" last="Costa">Paul T. Jr Costa</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>National Institute on Aging</s1><s3>USA</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Institute on Aging</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Health psychology : (Hillsdale, N.J.)</title><title level="j" type="abbreviated">Health psychol. : (Hillsdale, N.J.)</title><idno type="ISSN">0278-6133</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Health psychology : (Hillsdale, N.J.)</title><title level="j" type="abbreviated">Health psychol. : (Hillsdale, N.J.)</title><idno type="ISSN">0278-6133</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>AIDS</term><term>Big Five personality model</term><term>Cell subpopulation</term><term>Conscientiousness</term><term>Coping</term><term>Depression</term><term>Disease development</term><term>Drug compliance</term><term>Evolution</term><term>Follow up study</term><term>Helper cell</term><term>Human</term><term>Human immunodeficiency virus</term><term>Mental health</term><term>Personality</term><term>Predictive factor</term><term>Psychosocial factor</term><term>Stress</term><term>T-Lymphocyte</term><term>United States</term><term>Viral load</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Antigène CD4</term><term>Attitude consciencieuse</term><term>Cellule helper</term><term>Charge virale</term><term>Coping</term><term>Développement maladie</term><term>Etat dépressif</term><term>Etats Unis</term><term>Etude longitudinale</term><term>Evolution</term><term>Facteur prédictif</term><term>Développement maladie</term><term>Evolution</term><term>Facteur psychosocial</term><term>Homme</term><term>Lymphocyte T</term><term>Modèle en cinq facteurs de la personnalité</term><term>Observance médicamenteuse</term><term>Personnalité</term><term>SIDA</term><term>Santé mentale</term><term>Sous population cellulaire</term><term>Stress</term><term>Virus immunodéficience humaine</term><term>Personnalité</term><term>Charge virale</term><term>Lymphocyte T</term><term>Sous population cellulaire</term><term>Cellule helper</term><term>Stress</term><term>Coping</term><term>Etat dépressif</term><term>Observance médicamenteuse</term><term>Etude longitudinale</term><term>Santé mentale</term><term>Etats Unis</term><term>Homme</term><term>Facteur psychosocial</term><term>Antigène CD4</term><term>Attitude consciencieuse</term><term>Modèle en cinq facteurs de la personnalité</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term><term>Santé mentale</term><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective: Psychosocial factors (e.g., depression, avoidant coping, life stress) have been related to disease progression in HIV. This study examined the relationship between the Big Five Conscientiousness factor and HIV disease progression (CD4 cell and viral load) over 1 year in 119 seropositive participants. The study also examined whether Conscientiousness effects were mediated by adherence, perceived stress, depression, or coping measures. Design: In a 1-year longitudinal design, participants completed the NEO Five-Factor Inventory Conscientiousness scale (P. T. Costa & R. R. McCrae, 1992). Participants also completed psychosocial assessments and underwent blood draws at initial assessments and 1-year follow-up. Main Outcome Measures: Multiple hierarchical regression models were used to predict change in CD4 cell numbers and viral load log 10, controlling for demographic variables, initial disease status, and antiretroviral medications. Results: Conscientiousness predicted significant increases in CD4 number and significant decreases in viral load at 1 year. Conscientiousness was related positively to medication adherence and active coping and negatively to depression and perceived stress. Only perceived stress emerged as a possible mediator. Conclusion: The significant relationship between Conscientiousness and medication adherence, distress, and coping suggests that an assessment of Conscientiousness in patients with HIV may help specify or target behavioral interventions to promote optimal disease management.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="O Cleirigh, Conall" sort="O Cleirigh, Conall" uniqKey="O Cleirigh C" first="Conall" last="O'Cleirigh">Conall O'Cleirigh</name></noRegion><name sortKey="Costa, Paul T Jr" sort="Costa, Paul T Jr" uniqKey="Costa P" first="Paul T. Jr" last="Costa">Paul T. Jr Costa</name><name sortKey="Ironson, Gail" sort="Ironson, Gail" uniqKey="Ironson G" first="Gail" last="Ironson">Gail Ironson</name><name sortKey="Weiss, Alexander" sort="Weiss, Alexander" uniqKey="Weiss A" first="Alexander" last="Weiss">Alexander Weiss</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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